Plasmalogens

Plasmalogens are specialized phospholipids with unique antioxidant properties that make up 15-20% of brain cell membranes, playing crucial roles in nerve signal transmission and protecting brain cells from oxidative damage. Research shows they decline significantly with age and in neurodegenerative conditions like Alzheimer’s disease, with lower levels correlating with cognitive impairment. Clinical studies demonstrate that supplementation can increase blood plasmalogen levels and potentially improve cognitive function, mood, and mental concentration. Most adults take 100-300 mg daily for brain health support, with higher doses (200-300 mg) sometimes used for cognitive concerns. While naturally found in organ meats, shellfish, and dairy products, supplemental forms are typically derived from scallops or created as synthetic precursors that the body can convert to active plasmalogens. For optimal absorption, take with meals containing fat, as these are fat-soluble compounds.

Alternative Names: Ethanolamine Plasmalogens, PlsEtn, Ether Phospholipids, Vinyl Ether Phospholipids

Categories: Membrane Components, Neurological Support, Antioxidants

Primary Longevity Benefits


  • Brain health and cognitive function support
  • Neuroprotection against age-related decline
  • Cell membrane integrity and function
  • Antioxidant protection

Secondary Benefits


  • Potential support for Alzheimer’s disease management
  • Reduction of oxidative stress
  • Improved mood and mental concentration
  • Support for myelin formation and maintenance
  • Potential cardiovascular health benefits

Disclaimer: The information provided is for educational purposes only and is not intended as medical advice. Always consult with a healthcare professional before starting any supplement regimen, especially if you have pre-existing health conditions or are taking medications.

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